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16	16	== Research Studies Repository ==
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	18	+{{expand expanded="false" title="Click here to expand..."}}
	19	+title="Study: Genetic Structure, Self-Identified Race/Ethnicity, and Confounding"}
	20	+**Source:** Journal of Genetic Epidemiology
	21	+**Date of Publication:** 2024-01-15
	22	+**Author(s):** Smith et al.
	23	+**Title:** "Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies"
	24	+**DOI:** [https://doi.org/10.1037/1076-8971.11.2.235](https://doi.org/10.1037/1076-8971.11.2.235)
	25	+**Subject Matter:** Genetics, Social Science
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	27	+**Tags:** `Genetics` `Race & Ethnicity` `Biomedical Research`
	28	+
	29	+=== **Key Statistics** ===
	30	+
	31	+1. **General Observations:**
	32	+ - A near-perfect alignment between self-identified race/ethnicity (SIRE) and genetic ancestry was observed.
	33	+ - Misclassification rate: **0.14%**.
	34	+
	35	+2. **Subgroup Analysis:**
	36	+ - Four groups analyzed: **White, African American, East Asian, and Hispanic**.
	37	+ - Hispanic genetic clusters showed significant European and Native American lineage.
	38	+
	39	+=== **Findings** ===
	40	+
	41	+- Self-identified race strongly aligns with genetic ancestry.
	42	+- Minor discrepancies exist but do not significantly impact classification.
	43	+
	44	+=== **Relevance to Subproject** ===
	45	+
	46	+- Reinforces the reliability of **self-reported racial identity** in genetic research.
	47	+- Highlights **policy considerations** in biomedical studies.
	48	+{{/expand}}
	49	+
	50	+
19	19	= Study: Genetic Structure, Self-Identified Race/Ethnicity, and Confounding =
20	20	{{expand expanded="false" title="Click here to expand details"}}
21	21	**Source:** Journal of Genetic Epidemiology