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16	16	== Research Studies Repository ==
17	17
18		-{{expand expanded="false" title="Click here to expand..."}}
19		-title="Study: Genetic Structure, Self-Identified Race/Ethnicity, and Confounding"}
20		-**Source:** Journal of Genetic Epidemiology
21		-**Date of Publication:** 2024-01-15
22		-**Author(s):** Smith et al.
23		-**Title:** "Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies"
24		-**DOI:** [https://doi.org/10.1037/1076-8971.11.2.235](https://doi.org/10.1037/1076-8971.11.2.235)
25		-**Subject Matter:** Genetics, Social Science
26	26
27		-**Tags:** `Genetics` `Race & Ethnicity` `Biomedical Research`
28		-
29		-=== **Key Statistics** ===
30		-
31		-1. **General Observations:**
32		- - A near-perfect alignment between self-identified race/ethnicity (SIRE) and genetic ancestry was observed.
33		- - Misclassification rate: **0.14%**.
34		-
35		-2. **Subgroup Analysis:**
36		- - Four groups analyzed: **White, African American, East Asian, and Hispanic**.
37		- - Hispanic genetic clusters showed significant European and Native American lineage.
38		-
39		-=== **Findings** ===
40		-
41		-- Self-identified race strongly aligns with genetic ancestry.
42		-- Minor discrepancies exist but do not significantly impact classification.
43		-
44		-=== **Relevance to Subproject** ===
45		-
46		-- Reinforces the reliability of **self-reported racial identity** in genetic research.
47		-- Highlights **policy considerations** in biomedical studies.
48		-{{/expand}}
49		-
50		-
51	51	= Study: Genetic Structure, Self-Identified Race/Ethnicity, and Confounding =
52	52	{{expand expanded="false" title="Click here to expand details"}}
53	53	**Source:** Journal of Genetic Epidemiology