Changes for page Research at a Glance

Summary

• Page properties (1 modified, 0 added, 0 removed)

Details

Page properties

Content

...	...	@@ -47,35 +47,6 @@
47	47	- Highlights **policy considerations** in biomedical studies.
48	48	{{/expand}}
49	49
50		-title="Study: Genetic Structure, Self-Identified Race/Ethnicity, and Confounding"}
51		-**Source:** Journal of Genetic Epidemiology
52		-**Date of Publication:** 2024-01-15
53		-**Author(s):** Smith et al.
54		-**Title:** "Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies"
55		-**DOI:** [https://doi.org/10.1037/1076-8971.11.2.235](https://doi.org/10.1037/1076-8971.11.2.235)
56		-**Subject Matter:** Genetics, Social Science
57	57
58		-**Tags:** `Genetics` `Race & Ethnicity` `Biomedical Research`
59	59
60		-=== **Key Statistics** ===
61		-
62		-1. **General Observations:**
63		- - A near-perfect alignment between self-identified race/ethnicity (SIRE) and genetic ancestry was observed.
64		- - Misclassification rate: **0.14%**.
65		-
66		-2. **Subgroup Analysis:**
67		- - Four groups analyzed: **White, African American, East Asian, and Hispanic**.
68		- - Hispanic genetic clusters showed significant European and Native American lineage.
69		-
70		-=== **Findings** ===
71		-
72		-- Self-identified race strongly aligns with genetic ancestry.
73		-- Minor discrepancies exist but do not significantly impact classification.
74		-
75		-=== **Relevance to Subproject** ===
76		-
77		-- Reinforces the reliability of **self-reported racial identity** in genetic research.
78		-- Highlights **policy considerations** in biomedical studies.
79		-
80		-
81	81