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14	14	== Research Studies Repository ==
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17		-title="Study: Genetic Structure, Self-Identified Race/Ethnicity, and Confounding"}
18		-**Source:** Journal of Genetic Epidemiology
19		-**Date of Publication:** 2024-01-15
20		-**Author(s):** Smith et al.
21		-**Title:** "Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies"
22		-**DOI:** [https://doi.org/10.1037/1076-8971.11.2.235](https://doi.org/10.1037/1076-8971.11.2.235)
23		-**Subject Matter:** Genetics, Social Science
24		-
25		-**Tags:** `Genetics` `Race & Ethnicity` `Biomedical Research`
26		-
27		-=== **Key Statistics** ===
28		-1. **General Observations:**
29		- - A near-perfect alignment between self-identified race/ethnicity (SIRE) and genetic ancestry was observed.
30		- - Misclassification rate: **0.14%**.
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32		-2. **Subgroup Analysis:**
33		- - Four groups analyzed: **White, African American, East Asian, and Hispanic**.
34		- - Hispanic genetic clusters showed significant European and Native American lineage.
35		-
36		-=== **Findings** ===
37		-- Self-identified race strongly aligns with genetic ancestry.
38		-- Minor discrepancies exist but do not significantly impact classification.
39		-
40		-=== **Relevance to Subproject** ===
41		-- Reinforces the reliability of **self-reported racial identity** in genetic research.
42		-- Highlights **policy considerations** in biomedical studies.
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