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14	14	== Research Studies Repository ==
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	17	+title="Study: Genetic Structure, Self-Identified Race/Ethnicity, and Confounding"}
	18	+**Source:** Journal of Genetic Epidemiology
	19	+**Date of Publication:** 2024-01-15
	20	+**Author(s):** Smith et al.
	21	+**Title:** "Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies"
	22	+**DOI:** [https://doi.org/10.1037/1076-8971.11.2.235](https://doi.org/10.1037/1076-8971.11.2.235)
	23	+**Subject Matter:** Genetics, Social Science
	24	+
	25	+**Tags:** `Genetics` `Race & Ethnicity` `Biomedical Research`
	26	+
	27	+=== **Key Statistics** ===
	28	+1. **General Observations:**
	29	+ - A near-perfect alignment between self-identified race/ethnicity (SIRE) and genetic ancestry was observed.
	30	+ - Misclassification rate: **0.14%**.
	31	+
	32	+2. **Subgroup Analysis:**
	33	+ - Four groups analyzed: **White, African American, East Asian, and Hispanic**.
	34	+ - Hispanic genetic clusters showed significant European and Native American lineage.
	35	+
	36	+=== **Findings** ===
	37	+- Self-identified race strongly aligns with genetic ancestry.
	38	+- Minor discrepancies exist but do not significantly impact classification.
	39	+
	40	+=== **Relevance to Subproject** ===
	41	+- Reinforces the reliability of **self-reported racial identity** in genetic research.
	42	+- Highlights **policy considerations** in biomedical studies.
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